x1 = IR_beta x2 = IR_beta_pY1146 x3 = IR_beta_refractory x4 = IRS1 x5 = IRS1_p x6 = IRS1_pS636 x7 = AMPK x8 = AMPK_pT172 x9 = Akt_T308 x10 = Akt_pT308 x11 = Akt_S473 x12 = Akt_pS473 x13 = mTORC1 x14 = mTORC1_pS2448 x15 = mTORC2 x16 = mTORC2_pS2481 x17 = p70S6K x18 = p70S6K_pT389 x19 = PRAS40_T246 x20 = PRAS40_pT246 x21 = PRAS40_S183 x22 = PRAS40_pS183 x23 = TSC1_TSC2_pT1462 x24 = TSC1_TSC2_pS1387 x25 = PI3K_variant x26 = PI3K_variant_p x27 = Insulin x28 = Amino_Acids x29 = IR_beta_pY1146_obs x30 = IRS1_pS636_obs x31 = AMPK_pT172_obs x32 = Akt_pT308_obs x33 = Akt_pS473_obs x34 = TSC1_TSC2_pS1387_obs x35 = mTOR_pS2448_obs x36 = mTOR_pS2481_obs x37 = p70S6K_pT389_obs x38 = PRAS40_pT246_obs x39 = PRAS40_pS183_obs