D_SOS + EGFR_active -> A_SOS + EGFR_active
A_SOS + Ras -> A_SOS + Ras_active
EGFR_active -> 0
ERK + Mek_active -> ERK_active + Mek_active
A_SOS + P90Rsk_Active -> D_SOS + P90Rsk_Active
D_SOS + IGFR_active -> A_SOS + IGFR_active
IGFR_active + PI3KCA -> IGFR_active + PI3KCA_active
EGFR_active + PI3KCA -> EGFR_active + PI3KCA_active
AKT + PI3KCA_active -> AKT_active + PI3KCA_active
AKT_active -> AKT
ERK_active + PP2A -> ERK + PP2A
PI3KCA + Ras_active -> PI3KCA_active + Ras_active
Raf + Ras_active -> Raf_active + Ras_active
Mek + Raf_active -> Mek_active + Raf_active
AKT_active + Raf_active -> AKT_active + Raf
RasGapActive + Ras_active -> Ras + RasGapActive
Mek_active + PP2A -> Mek + PP2A
IGFR_active -> 0
PI3KCA_active -> PI3KCA
RafPP + Raf_active -> Raf + RafPP
ERK_active + P90RskInactive -> ERK_active + P90Rsk_Active
P90Rsk_Active -> P90RskInactive