Recptor + agonist -> DR DR -> Recptor + agonist DR + G_GDP -> DRG_GDP DRG_GDP -> DR + G_GDP DRG_GDP -> DRG + GDP DRG + GDP -> DRG_GDP DRG + GTP -> DRG_GTP DRG_GTP -> DRG + GTP DRG_GTP -> DR + G_GTP G_GTP -> G_GDP