IR_beta -> IR_beta_pY1146 IR_beta_pY1146 -> IR_beta_refractory IR_beta_refractory -> IR_beta IRS1 -> IRS1_p IRS1_p -> IRS1_pS636 IRS1_pS636 -> IRS1 AMPK -> AMPK_pT172 AMPK_pT172 -> AMPK Akt_pT308 -> Akt_T308 Akt_pS473 -> Akt_S473 Akt_S473 -> Akt_pS473 Akt_T308 -> Akt_pT308 mTORC1_pS2448 -> mTORC1 mTORC1 -> mTORC1_pS2448 mTORC2_pS2481 -> mTORC2 mTORC2 -> mTORC2_pS2481 p70S6K_pT389 -> p70S6K p70S6K -> p70S6K_pT389 PRAS40_pS183 -> PRAS40_S183 PRAS40_pT246 -> PRAS40_T246 PRAS40_S183 -> PRAS40_pS183 PRAS40_T246 -> PRAS40_pT246 TSC1_TSC2_pT1462 -> TSC1_TSC2_pS1387 TSC1_TSC2_pS1387 -> TSC1_TSC2_pT1462 PI3K_variant_p -> PI3K_variant PI3K_variant -> PI3K_variant_p