GLCex <-> G6P
G6P + pAkt <-> F16P + pAkt
F16P -> PYRin
PYRin <-> LAC
PYRout <-> PYRin
PYRin -> OAA
OAA + PEPCK -> F16P + PEPCK
G6P + pAkt <-> G1P + pAkt
G1P + pGP <-> GLY + pGP
G6P + pGP -> G6P + GP
0 -> IRS
IRS <-> p1IRS
p1IRS -> 0
p1IRS + pmTOR -> p1p2IRS + pmTOR
p1p2IRS -> p1IRS
IRS + pmTOR -> p2IRS + pmTOR
p2IRS -> IRS
p2IRS -> 0
p2IRS <-> p1p2IRS
p1p2IRS -> 0
Akt + p1IRS -> p1IRS + pAkt
pAkt -> Akt
mTOR + pAkt -> pAkt + pmTOR
pmTOR -> mTOR
Foxo + pAkt -> pAkt + pFoxo
Foxo -> Foxo + mRNA
mRNA -> PEPCK + mRNA
pFoxo -> Foxo
GP -> pGP