S4_c <-> S4_n S2_c <-> S2_n pS2_c <-> pS2_n R_act + S2_c -> R_act + pS2_c S4_c + pS2_c <-> S24_c S4_n + pS2_n <-> S24_n S24_c -> S24_n S22_c -> S22_n 2*pS2_c <-> S22_c 2*pS2_n <-> S22_n PPase + pS2_n -> PPase + S2_n R + TGFb_c -> R_act R_act + SB <-> R_inact G_c + R_act -> R_act + pG_c PPase + pG_n -> G_n + PPase G_c <-> G_n pG_c <-> pG_n 2*pG_c <-> GG_c 2*pG_n <-> GG_n pG_c + pS2_c <-> G2_c pG_n + pS2_n <-> G2_n S4_c + pG_c <-> G4_c S4_n + pG_n <-> G4_n GG_c -> GG_n G2_c -> G2_n G4_c -> G4_n