[ Eq(Derivative(x1, t), (1*k1*(k2*k89*x2 - k3*x1) + (-1)*k1*k36*x1)/k1),
  Eq(Derivative(x2, t), ((-1)*k1*(k2*k89*x2 - k3*x1) + 1*k1*k46 + (-1)*k1*k47*x2)/k1),
  Eq(Derivative(x3, t), (1*k1*k4*x1*x4/(k5 + x4) + (-1)*k1*k25*x13*x3/(k26 + x3) + (-1)*k1*k77*x11*x3/(k78 + x3))/k1),
  Eq(Derivative(x4, t), ((-1)*k1*k4*x1*x4/(k5 + x4) + 1*k1*k25*x13*x3/(k26 + x3) + 1*k1*k77*x11*x3/(k78 + x3))/k1),
  Eq(Derivative(x5, t), (1*k1*k6*x3*x6/(k7 + x6) + (-1)*k1*k8*k92*x5/(k9 + x5))/k1),
  Eq(Derivative(x6, t), ((-1)*k1*k6*x3*x6/(k7 + x6) + 1*k1*k8*k92*x5/(k9 + x5))/k1),
  Eq(Derivative(x7, t), (1*k1*k10*x5*x8/(k11 + x8) + (-1)*k1*k12*k91*x7/(k13 + x7) + (-1)*k1*k34*x17*x7/(k35 + x7))/k1),
  Eq(Derivative(x8, t), ((-1)*k1*k10*x5*x8/(k11 + x8) + 1*k1*k12*k91*x7/(k13 + x7) + 1*k1*k34*x17*x7/(k35 + x7))/k1),
  Eq(Derivative(x9, t), (1*k1*k14*x7*x10/(k15 + x10) + (-1)*k1*k16*k90*x9/(k17 + x9) + 1*k1*k44*x45*x10/(k45 + x10))/k1),
  Eq(Derivative(x10, t), ((-1)*k1*k14*x7*x10/(k15 + x10) + 1*k1*k16*k90*x9/(k17 + x9) + (-1)*k1*k44*x45*x10/(k45 + x10))/k1),
  Eq(Derivative(x11, t), (1*k1*k18*x9*x12/(k19 + x12) + (-1)*k1*k20*k90*x11/(k21 + x11) + (-1)*k1*k75*x7*x11/(k76 + x11))/k1),
  Eq(Derivative(x12, t), ((-1)*k1*k18*x9*x12/(k19 + x12) + 1*k1*k20*k90*x11/(k21 + x11) + 1*k1*k75*x7*x11/(k76 + x11))/k1),
  Eq(Derivative(x13, t), (1*k1*k22*x11*x14/(k23 + x14) + (-1)*k1*k24*x13)/k1),
  Eq(Derivative(x14, t), ((-1)*k1*k22*x11*x14/(k23 + x14) + 1*k1*k24*x13)/k1),
  Eq(Derivative(x15, t), (1*k1*k27*x1*x16/(k28 + x16) + 1*k1*k29*x5*x16/(k30 + x16) + (-1)*k1*k31*x15 + 1*k1*k54*x32*x16/(k55 + x16))/k1),
  Eq(Derivative(x16, t), ((-1)*k1*k27*x1*x16/(k28 + x16) + (-1)*k1*k29*x5*x16/(k30 + x16) + 1*k1*k31*x15 + (-1)*k1*k54*x32*x16/(k55 + x16))/k1),
  Eq(Derivative(x17, t), (1*k1*k32*x15*x18/(k33 + x18) + 1*k1*k52*x29*x18/(k53 + x18) + 1*k1*k61*x35*x18/(k62 + x18) + 1*k1*k63*k96*x18/(k64 + x18) + (-1)*k1*k65*k97*x17/(k66 + x17) + 1*k1*k67*k98*x18/(k68 + x18) + 1*k1*k69*k99*x18/(k70 + x18) + (-1)*k1*k71*k100*x17/(k72 + x17) + (-1)*k1*k73*k90*x17/(k74 + x17))/k1),
  Eq(Derivative(x18, t), ((-1)*k1*k32*x15*x18/(k33 + x18) + (-1)*k1*k52*x29*x18/(k53 + x18) + (-1)*k1*k61*x35*x18/(k62 + x18) + (-1)*k1*k63*k96*x18/(k64 + x18) + 1*k1*k65*k97*x17/(k66 + x17) + (-1)*k1*k67*k98*x18/(k68 + x18) + (-1)*k1*k69*k99*x18/(k70 + x18) + 1*k1*k71*k100*x17/(k72 + x17) + 1*k1*k73*k90*x17/(k74 + x17))/k1),
  Eq(Derivative(x19, t), (1*k1*k37*x1*x20/(k38 + x20) + (-1)*k1*k39*x19)/k1),
  Eq(Derivative(x20, t), ((-1)*k1*k37*x1*x20/(k38 + x20) + 1*k1*k39*x19)/k1),
  Eq(Derivative(x21, t), (1*k1*k40*x19*x22/(k41 + x22) + (-1)*k1*k42*k93*x21/(k43 + x21))/k1),
  Eq(Derivative(x22, t), ((-1)*k1*k40*x19*x22/(k41 + x22) + 1*k1*k42*k93*x21/(k43 + x21))/k1),
  Eq(Derivative(x23, t), 0),
  Eq(Derivative(x24, t), 0),
  Eq(Derivative(x25, t), 0),
  Eq(Derivative(x26, t), 0),
  Eq(Derivative(x27, t), 0),
  Eq(Derivative(x28, t), 0),
  Eq(Derivative(x29, t), (1*k1*k48*x15*x30/(k49 + x30) + (-1)*k1*k50*k95*x29/(k51 + x29))/k1),
  Eq(Derivative(x30, t), ((-1)*k1*k48*x15*x30/(k49 + x30) + 1*k1*k50*k95*x29/(k51 + x29))/k1),
  Eq(Derivative(x31, t), 0),
  Eq(Derivative(x32, t), (1*k1*k56*x1*x33/(k57 + x33) + (-1)*k1*k83*x43*x32/(k84 + x32))/k1),
  Eq(Derivative(x33, t), ((-1)*k1*k56*x1*x33/(k57 + x33) + 1*k1*k83*x43*x32/(k84 + x32))/k1),
  Eq(Derivative(x34, t), ((-1)*k1*k58*x29*x34/(k59 + x34) + 1*k1*k60*x35)/k1),
  Eq(Derivative(x35, t), (1*k1*k58*x29*x34/(k59 + x34) + (-1)*k1*k60*x35)/k1),
  Eq(Derivative(x36, t), 0),
  Eq(Derivative(x37, t), 0),
  Eq(Derivative(x38, t), 0),
  Eq(Derivative(x39, t), 0),
  Eq(Derivative(x40, t), 0),
  Eq(Derivative(x41, t), 1*k1*k79*x17*x42/(k80 + x42)/k1),
  Eq(Derivative(x42, t), (-1)*k1*k79*x17*x42/(k80 + x42)/k1),
  Eq(Derivative(x43, t), 1*k1*k81*x41*x44/(k82 + x44)/k1),
  Eq(Derivative(x44, t), (-1)*k1*k81*x41*x44/(k82 + x44)/k1),
  Eq(Derivative(x45, t), ((-1)*k1*k86*x46*x45/(k87 + x45) + 1*k1*k88)/k1),
  Eq(Derivative(x46, t), (-1)*k1*k85*x46/k1),
  Eq(Derivative(x47, t), 1*k1*k86*x46*x45/(k87 + x45)/k1),
  Eq(Derivative(x48, t), 0) ]