[ Eq(Derivative(x1, t), ((-1)*k138*k153 + (-1)*k91*x1*x4/(x4 + k7*k153) + (-1)*k32*x1*x39/(x39 + k77*x33 + k21*k153)*x5/(k9*k153 + x4 + x5) + (-1)*k43*x1*x29/(k27 + x29) + 1*k31*x2*x35/(x35 + k20*k153) + 1*k128*k153 + 1*k100*x2 + 1*k100*k161*x3 + 1*x29*k153*k111*k110/(k19 + x29)/(k26 + x29/(k19 + x29)) + (-1)*k46*x1 + (-1)*k32*x39*x1/(x39 + k77*x33 + k21*k153)*x4/(k9*k153 + x4 + x5))/k279),
  Eq(Derivative(x2, t), (1*k32*x1*x39/(x39 + k77*x33 + k21*k153)*x4/(k9*k153 + x4 + x5) + 1*k32*x1*x39/(x39 + k77*x33 + k21*k153)*x5/(k9*k153 + x4 + x5) + 1*k43*x1*x29/(k27 + x29) + (-1)*k47*x2 + (-1)*k31*x2*x35/(x35 + k20*k153))/k279),
  Eq(Derivative(x3, t), (1*k91*x1*x4/(x4 + k7*k153) + (-1)*k135*k153 + (-1)*k92*x3/((x5/x3)**2 + k93**2)*(x5/x3)**2 + (-1)*x3/k153*x8*k153*k1/x3/(x8/x3 + k8*k153))/k279),
  Eq(Derivative(x4, t), ((-1)*k6*x4*x51/k153 + 1*k6*x52/k97 + (-1)*k6*x4*x23/k153 + 1*k6*x51/k97 + (-1)*k151*k153 + 1*k98*x4 + 1*(k153*x5*k135/x3 + k92*x3*1/((x5/x3)**2 + k93**2)*x5/x3*(x5/x3)**2) + 1*x3*x5/k153/x3*x8*k153*k1/x3/(x8/x3 + k8*k153) + (-1)*x2*x4*k2/k153 + (-1)*x1*x4*k3/k153 + (-1)*x4*x6*k94/k153 + (-25)*k91*x1*x4/(x4 + k7*k153))/k279),
  Eq(Derivative(x5, t), (1*x3*x1*x4*25*k91/(x4 + k7*k153)/x3 + 1*k99*x3*x5/x3 + (-1)*(k99*x3*x5*(x5/x3)**2/((x5/x3)**2 + k93**2)/x3 + x3*x5*k153*k135/x3/x3 + x3*x5*x3/x3*(x5/x3)**2*k92/((x5/x3)**2 + k93**2)/x3) + (-1)*x3*x5*x3/x3*x8*k1/x3/(x8/x3 + k8*k153)/x3)/k279),
  Eq(Derivative(x6, t), ((-1)*k81*x6*x4/(k11*k153 + x4) + 1*k129*k153 + 1*k153*x4*k101/(k10*k153 + x4) + 1*(x29*k153*k131*k110/(k19 + x29)/(k26 + x29/(k19 + x29)) + x29*k153*k133*k110/(k19 + x29)/(k26 + x29/(k19 + x29))) + (-1)*k49*x6 + (-1)*x6/k153*x29*k153*k110*k81/(k19 + x29)/(k26 + x29/(k19 + x29)))/k279),
  Eq(Derivative(x7, t), (1*k83*x13*x2/(k13*k153 + x2) + (-1)*k35*x7*x33/(x33 + k79*x39 + k24*k153) + (-1)*x36*x38*k34/k153*x7/(x36 + k78*x33 + k80*x35 + k22*k153) + (-1)*k44*x1*x30*x7/(10000000 + x30) + 1*k104*x7*x2/(k14*k153 + x2) + (-1)*k52*x7 + (-1)*k44*x2*x7*x30/(10000000 + x30))/k279),
  Eq(Derivative(x8, t), (1*x36*x38*k34/k153*x7/(x36 + k78*x33 + k80*x35 + k22*k153) + 1*k44*x1*x30*x7/(10000000 + x30) + 1*k44*x2*x30*x7/(10000000 + x30) + 1*x8*x8/k153*x29*k153*k109/(k19 + x29)/(k25 + x8*x29/(k19 + x29)) + (-1)*k53*x8)/k279),
  Eq(Derivative(x9, t), ((-1)*k84*x9 + 1*k35*x7*x33/(x33 + k79*x39 + k24*k153) + (-1)*k136*k153)/k279),
  Eq(Derivative(x10, t), (1*k81*x6*x4/(k11*k153 + x4) + 1*x6/k155/k153*x29*k155*k153*k110*k81/(k19 + x29)/(k26 + x29/(k19 + x29)) + (-1)*k50*x10)/k279),
  Eq(Derivative(x11, t), ((-1)*k133*k155 + (-1)*x10*x11*k40/k155 + (-1)*k131*k155 + (-1)*x10*x11*k33/k155 + 1*k130*k155 + 1*k102*x10 + (-1)*k51*x11)/k279),
  Eq(Derivative(x12, t), ((-1)*k82*x12 + 1*k131*k155 + 1*x10*x11*k33/k155 + 1*x12*k103/(k12 + (x12/k155)**2))/k279),
  Eq(Derivative(x13, t), (1*k82*x12 + (-1)*k83*x13*x2/(k13*k153 + x2) + (-1)*k71*x13)/k279),
  Eq(Derivative(x14, t), ((-1)*k85*x14 + 1*k84*x9)/k279),
  Eq(Derivative(x15, t), (1*k85*x14 + (-1)*k55*x15)/k279),
  Eq(Derivative(x16, t), ((-1)*k36*x16*x44/(x43 + x44 + 1/100000) + 1*k132*k152 + 1*k58*x19 + (-1)*k56*x16*x43/(x43 + x44 + 1/100000))/k279),
  Eq(Derivative(x17, t), ((-1)*k86*x17 + 1*k36*x16*x44/(x43 + x44 + 1/100000))/k279),
  Eq(Derivative(x18, t), (1*k86*x17 + 1*k137*k154 + (-1)*k87*x18 + -1/2*k37*x18*x47/(x47 + x48 + 1/100000))/k279),
  Eq(Derivative(x19, t), (1/2*k37*x18*x47/(x47 + x48 + 1/100000) + (-2)*k58*x19)/k279),
  Eq(Derivative(x20, t), ((-1)*k137*k154 + 1*k87*x18 + -1/2*k39*x20*x47/(x47 + x48 + 1/100000) + 1*k106*x20*x48/(x47 + x48 + 1/100000) + (-1)*k59*x20)/k279),
  Eq(Derivative(x21, t), (1/2*k39*x20*x47/(x47 + x48 + 1/100000) + (-1)*k57*x21)/k279),
  Eq(Derivative(x22, t), ((-1)*k6*x41*x22/k152 + 1*k6*x49/k97 + (-1)*k112*x22 + 1*k152*x23*k112/k153 + 1000000*x18 + 1000000*x20 + 1000000*x21 + (-1)*k60*x22)/k279),
  Eq(Derivative(x23, t), ((-1)*k6*x4*x23/k153 + 1*k6*x51/k97 + 1*k112*x22 + (-1)*k152*x23*k112/k153)/k279),
  Eq(Derivative(x24, t), ((-1)*k89*x24 + 1*k133*k155 + 1*x10*x11*k40/k155)/k279),
  Eq(Derivative(x25, t), ((-1)*k90*x25*x2/(k15*k153 + x2) + 1*k89*x24 + (-1)*k72*x25)/k279),
  Eq(Derivative(x26, t), ((-1)*x26*x29*k41/k153 + 1*k90*x25*x2/(k15*k153 + x2) + (-1)*k61*x26)/k279),
  Eq(Derivative(x27, t), (1*x26*x29*k41/k153 + 1*x8*x27/k153*x29*k153*k107/(k19 + x29)/(k19 + x8*x29/(k19 + x29)) + (-1)*k62*x27)/k279),
  Eq(Derivative(x28, t), (1*k138*k153 + (-1)*k139*k153)/k279),
  Eq(Derivative(x29, t), ((-1)*k64*x29 + (-1)*k4*x2*x29/(100000 + x29) + (-1)*k4*x27*x29/(100000 + x29) + 1*k140*k153)/k279),
  Eq(Derivative(x30, t), ((-1)*k114*x30 + 1*k153*x41*k114/k152 + 1*k64*x29 + 1*k4*x2*x29/(100000 + x29) + 1*k4*x27*x29/(100000 + x29) + (-1)*k95*x30)/k279),
  Eq(Derivative(x31, t), (1*k141*k153 + (-1)*k142*k153)/k279),
  Eq(Derivative(x32, t), (1*k143*k153 + (-1)*k144*k153)/k279),
  Eq(Derivative(x33, t), (1*k116*x7 + 1*k117*x9 + (-1)*k65*x33)/k279),
  Eq(Derivative(x34, t), (1*k145*k154 + (-1)*k146*k154)/k279),
  Eq(Derivative(x35, t), (1*k17*k118*x2*1/(x35 + k28*x39 + k17*k153) + 1*k119*x8 + 1*k120*x9 + 1*k121*x7 + 1*k122*x3 + (-1)*k66*x35)/k279),
  Eq(Derivative(x36, t), (1*k123*x10 + (-1)*(k67*x36 + k147*k155))/k279),
  Eq(Derivative(x37, t), (1*k147*k152 + (-1)*k148*k152)/k279),
  Eq(Derivative(x38, t), (1*k148*k153 + 1*k124*x1 + 1*k125*x2 + (-1)*k68*x38)/k279),
  Eq(Derivative(x39, t), (1*(k134*k153*x38*x4/(k29*k153 + x38)/(k18*k153 + x4 + x5) + k134*k153*x38*x5/(k29*k153 + x38)/(k18*k153 + x4 + x5)) + 1*k153*x2*x8*k126/(k30*k153 + x2) + (-1)*k69*x39)/k279),
  Eq(Derivative(x40, t), (1*k149*k153 + (-1)*k150*k153)/k279),
  Eq(Derivative(x41, t), ((-1)*k6*x41*x49/k152 + 1*k6*x50/k97 + (-1)*k6*x41*x22/k152 + 1*k6*x49/k97 + (-1)*k6*x41*x47/k152 + 1*k6*x48/k96 + (-1)*k115*x41 + 1*k115*x42 + 1*k151*k153 + 1*k114*x30 + (-1)*k153*x41*k114/k152)/k279),
  Eq(Derivative(x42, t), ((-1)*k6*x42*x45/k152 + 1*k6*x46/k96 + (-1)*k6*x42*x43/k152 + 1*k6*x44/k96 + 1*k115*x41 + (-1)*k115*x42)/k279),
  Eq(Derivative(x43, t), ((-1000)*k36*x16*x44/(x43 + x44 + 1/100000) + (-1)*k6*x42*x43/k152 + 1*k6*x44/k96 + 1000*k132*k152 + 1000*k58*x19 + (-1000)*k56*x16*x43/(x43 + x44 + 1/100000))/k279),
  Eq(Derivative(x44, t), (1*k6*x42*x43/k152 + (-1)*k6*x44/k96)/k279),
  Eq(Derivative(x45, t), ((-1000)*k86*x17 + (-1)*k6*x42*x45/k152 + 1*k6*x46/k96 + 1000*k36*x16*x44/(x43 + x44 + 1/100000))/k279),
  Eq(Derivative(x46, t), (1*k6*x42*x45/k152 + (-1)*k6*x46/k96)/k279),
  Eq(Derivative(x47, t), ((-1)*k6*x41*x47/k152 + 1*k6*x48/k96 + 1000*k86*x17 + 1000*k137*k154 + (-1000)*k87*x18 + (-500)*k37*x18*x47/(x47 + x48 + 1/100000))/k279),
  Eq(Derivative(x48, t), (1*k6*x41*x47/k152 + (-1)*k6*x48/k96)/k279),
  Eq(Derivative(x49, t), ((-1)*k6*x41*x49/k152 + 1*k6*x50/k97 + 1*k6*x41*x22/k152 + (-1)*k6*x49/k97 + (-1)*k73*x49)/k279),
  Eq(Derivative(x50, t), (1*k6*x41*x49/k152 + (-1)*k6*x50/k97 + (-1)*k74*x50)/k279),
  Eq(Derivative(x51, t), ((-1)*k6*x4*x51/k153 + 1*k6*x52/k97 + 1*k6*x4*x23/k153 + (-1)*k6*x51/k97 + (-1)*k75*x51)/k279),
  Eq(Derivative(x52, t), (1*k6*x4*x51/k153 + (-1)*k6*x52/k97 + (-1)*k76*x52)/k279) ]