[ Eq(Derivative(x1, t), ((-1)*k3*x1 + 1*k80*x43)/k1),
  Eq(Derivative(x2, t), (1*k3*x1 + (-1)*k4*x2)/k1),
  Eq(Derivative(x3, t), (1*k4*x2 + (-1)*k6*x3/(k5 + x3) + (-1)*k7*x3/(k8 + x3) + (-1)*k24*x3/(k23 + x3))/k1),
  Eq(Derivative(x4, t), (1*k10*x5/(k9 + x5) + (-1)*k15*x4/(k14 + x4))/k1),
  Eq(Derivative(x5, t), (1*k6*x3/(k5 + x3) + (-1)*k10*x5/(k9 + x5) + 1*k35*x18/(k36 + x18))/k1),
  Eq(Derivative(x6, t), ((-1)*k12*x6/(k11 + x6) + 1*k15*x4/(k14 + x4) + 1*k56*x27/(k57 + x27))/k1),
  Eq(Derivative(x7, t), (1*k12*x6/(k11 + x6) + (-1)*k13*x7)/k1),
  Eq(Derivative(x8, t), (1*k7*x3/(k8 + x3) + (-1)*k16*x8/(k17 + x8))/k1),
  Eq(Derivative(x9, t), (1*k16*x8/(k17 + x8) + (-1)*k18*x9/(k19 + x9) + 1*k42*x18/(k43 + x18) + 1*k70*x31/(k71 + x31))/k1),
  Eq(Derivative(x10, t), (1*k18*x9/(k19 + x9) + (-1)*k20*x10)/k1),
  Eq(Derivative(x11, t), (1*k24*x3/(k23 + x3) + (-1)*k25*x11/(k26 + x11))/k1),
  Eq(Derivative(x12, t), ((-1)*k27*x12 + 1*k46*x21/(k47 + x21))/k1),
  Eq(Derivative(x13, t), (-1)*k30*x13/k1),
  Eq(Derivative(x14, t), (1*k30*x13 + (-1)*k31*x14)/k1),
  Eq(Derivative(x15, t), (1*k31*x14 + (-1)*k32*x15)/k1),
  Eq(Derivative(x16, t), (1*k32*x15 + (-1)*k33*x16)/k1),
  Eq(Derivative(x17, t), (1*k33*x16 + (-1)*k34*x17)/k1),
  Eq(Derivative(x18, t), (1*k34*x17 + (-1)*k35*x18/(k36 + x18) + (-1)*k37*x18/(k38 + x18) + (-1)*k42*x18/(k43 + x18) + (-1)*k44*x18/(k45 + x18))/k1),
  Eq(Derivative(x19, t), (1*k37*x18/(k38 + x18) + (-1)*k39*x19/(k40 + x19) + 1*k68*x32/(k69 + x32))/k1),
  Eq(Derivative(x20, t), (1*k39*x19/(k40 + x19) + (-1)*k41*x20)/k1),
  Eq(Derivative(x21, t), (1*k25*x11/(k26 + x11) + 1*k44*x18/(k45 + x18) + (-1)*k46*x21/(k47 + x21))/k1),
  Eq(Derivative(x22, t), (-1)*k48*x22/k1),
  Eq(Derivative(x23, t), (1*k48*x22 + (-1)*k49*x23/(k50 + x23) + (-1)*k58*x23/(k59 + x23) + (-1)*k63*x23 + (-1)*k72*x23/(k73 + x23))/k1),
  Eq(Derivative(x24, t), (1*k49*x23/(k50 + x23) + (-1)*k51*x24/(k52 + x24))/k1),
  Eq(Derivative(x25, t), (1*k51*x24/(k52 + x24) + (-1)*k53*x25/(k54 + x25))/k1),
  Eq(Derivative(x26, t), (1*k53*x25/(k54 + x25) + (-1)*k55*x26)/k1),
  Eq(Derivative(x27, t), (1*k55*x26 + (-1)*k56*x27/(k57 + x27) + (-1)*k81*x27/(k82 + x27) + (-1)*k83*x27/(k84 + x27))/k1),
  Eq(Derivative(x28, t), (1*k58*x23/(k59 + x23) + (-1)*k60*x28/(k61 + x28))/k1),
  Eq(Derivative(x29, t), (1*k60*x28/(k61 + x28) + (-1)*k62*x29)/k1),
  Eq(Derivative(x30, t), (1*k63*x23 + (-1)*k64*x30/(k65 + x30))/k1),
  Eq(Derivative(x31, t), (1*k64*x30/(k65 + x30) + (-1)*k66*x31/(k67 + x31) + (-1)*k70*x31/(k71 + x31) + 1*k81*x27/(k82 + x27))/k1),
  Eq(Derivative(x32, t), (1*k66*x31/(k67 + x31) + (-1)*k68*x32/(k69 + x32) + 1*k83*x27/(k84 + x27))/k1),
  Eq(Derivative(x33, t), (1*k72*x23/(k73 + x23) + (-1)*k74*x33/(k75 + x33))/k1),
  Eq(Derivative(x34, t), (1*k74*x33/(k75 + x33) + (-1)*k76*x34)/k1),
  Eq(Derivative(x35, t), (1*k13*x7 + (-1)*k77*x35**k78/(k79 + x35**k78))/k2),
  Eq(Derivative(x36, t), (1*k20*x10 + (-1)*k21*x36/(k22 + x36))/k2),
  Eq(Derivative(x37, t), 1*k21*x36/(k22 + x36)/k2),
  Eq(Derivative(x38, t), (1*k27*x12 + (-1)*k28*x38/(k29 + x38))/k2),
  Eq(Derivative(x39, t), 1*k28*x38/(k29 + x38)/k2),
  Eq(Derivative(x40, t), 1*k41*x20/k2),
  Eq(Derivative(x41, t), 1*k62*x29/k2),
  Eq(Derivative(x42, t), 1*k76*x34/k2),
  Eq(Derivative(x43, t), (1*k77*x35**k78/(k79 + x35**k78) + (-1)*k80*x43)/k2) ]