[ Eq(Derivative(x1, t), (1*k2 + (-1)*k4*x1*(1 + x1)*(1 + x2)**2/(k3 + (1 + x1)**2*(1 + x2)**2))/k1),
  Eq(Derivative(x2, t), (50*k4*x1*(1 + x1)*(1 + x2)**2/(k3 + (1 + x1)**2*(1 + x2)**2) + (-1)*k7*x2*(1 + k6*x2)*(1 + x3)**2/(k5 + (1 + k6*x2)**2*(1 + x3)**2))/k1),
  Eq(Derivative(x3, t), (1/50*k7*x2*(1 + k6*x2)*(1 + x3)**2/(k5 + (1 + k6*x2)**2*(1 + x3)**2) + (-1)*k8*x3)/k1) ]