[ Eq(Derivative(x1, t), k1*k4**k39/(k4**k39 + x2**k39) - (k2*x1/(k3 + x1) + k22*x1)),
  Eq(Derivative(x2, t), k18*x3 - (k19*x2 + k17*x2)),
  Eq(Derivative(x3, t), k20*x10*x4 + k19*x2 - (k21*x3 + k18*x3 + k16*x3)),
  Eq(Derivative(x4, t), k28*x5/(k36 + x5) + k21*x3 - (k30*x4/(k38 + x4) + k20*x10*x4 + k14*x4/(k15 + x4) + k22*x4)),
  Eq(Derivative(x5, t), k24*x6/(k32 + x6) + k30*x4/(k38 + x4) - (k26*x5/(k34 + x5) + k28*x5/(k36 + x5) + k22*x5)),
  Eq(Derivative(x6, t), k13*x7 + k26*x5/(k34 + x5) - (k24*x6/(k32 + x6) + k22*x6)),
  Eq(Derivative(x7, t), k9*k12**k39/(k12**k39 + x2**k39) - (k10*x7/(k11 + x7) + k22*x7)),
  Eq(Derivative(x8, t), k6*x1 + k25*x9/(k33 + x9) - (k23*x8/(k31 + x8) + k22*x8)),
  Eq(Derivative(x9, t), k23*x8/(k31 + x8) + k29*x10/(k37 + x10) - (k25*x9/(k33 + x9) + k27*x9/(k35 + x9) + k22*x9)),
  Eq(Derivative(x10, t), k27*x9/(k35 + x9) + k21*x3 - (k29*x10/(k37 + x10) + k20*x10*x4 + k7*x10/(k8 + x10) + k22*x10)) ]