[ Eq(Derivative(x3, t), 0),
  Eq(Derivative(x4, t), 0),
  Eq(Derivative(x5, t), 0),
  Eq(Derivative(x6, t), 0),
  Eq(Derivative(x7, t), 0),
  Eq(Derivative(x8, t), 0),
  Eq(Derivative(x9, t), 0),
  Eq(Derivative(x10, t), 0),
  Eq(Derivative(x11, t), (1*k161*k71*x13*x34/((k72 + x13)*(k73 + x34))*(k74 + k75)/(k169 + k75) + 1*k161*k76*x17*k165/((k77 + x17)*(k78 + k165)) + 1*k161*k79*x16/(k30 + x16) + 1*k161*k80*x16*k164/((k81 + x16)*(k82 + k164)) + (-1)*k161*k83*x11*x39/((k84 + x11)*(k85 + x39)) + (-1)*k161*(k86*x11*x35/((k32 + x11)*(k33 + x35)) - k87*x30*x14/((k35 + x30)*(k36 + x14))) + (-1)*k161*(k88*x11*k171 - k89*x14) + 1*k161*k99*x16*x26/((k100 + x16)*(k101 + x26)))/k161),
  Eq(Derivative(x12, t), (1*k162*k29*x20/(k30 + x20) + (-1)*k162*(k31*x12*x40/((k32 + x12)*(k33 + x40)) - k34*x41*x18/((k35 + x41)*(k36 + x18))) + (-1)*k162*(k37*x12*x42/((k38 + x12)*(k39 + x42)) - k40*x20/(k41 + x20)) + (-1)*k162*(k42*x12*k171 - k43*x18) + (-1)*k162*k44*x12*x41/((k45 + x12)*(k46 + x41)) + (-1)*k162*k47*x12*x43/((k48 + x12)*(k49 + x43)) + (-1)*k162*k50*x12*x44/((k51 + x12)*(k52 + x44)))/k162),
  Eq(Derivative(x13, t), ((-1)*k161*k71*x13*x34/((k72 + x13)*(k73 + x34))*(k74 + k75)/(k169 + k75) + 1*k161*k93*x14*k165/((k94 + x14)*(k95 + k165))*72/(10 + x37 - x36))/k161),
  Eq(Derivative(x14, t), (1*k161*(k86*x11*x35/((k32 + x11)*(k33 + x35)) - k87*x30*x14/((k35 + x30)*(k36 + x14))) + 1*k161*(k88*x11*k171 - k89*x14) + (-1)*k161*k90*k167*x14/((k91 + k167)*(k92 + x14)) + (-1)*k161*k93*x14*k165/((k94 + x14)*(k95 + k165))*72/(10 + x37 - x36) + (-1)*k161*(k96*x14/(k54 + x14) - k97*x15/(k56 + x15)))/k161),
  Eq(Derivative(x15, t), (1*k161*(k96*x14/(k54 + x14) - k97*x15/(k56 + x15)) + (-1)*k161*(k98*x15/(k58 + x15) - k59*x16/(k60 + x16)))/k161),
  Eq(Derivative(x16, t), ((-1)*k161*k79*x16/(k30 + x16) + (-1)*k161*k80*x16*k164/((k81 + x16)*(k82 + k164)) + 1*k161*k83*x11*x39/((k84 + x11)*(k85 + x39)) + 1*k161*(k98*x15/(k58 + x15) - k59*x16/(k60 + x16)) + (-1)*k161*k99*x16*x26/((k100 + x16)*(k101 + x26)))/k161),
  Eq(Derivative(x17, t), ((-1)*k161*k76*x17*k165/((k77 + x17)*(k78 + k165)) + 1*k161*k90*k167*x14/((k91 + k167)*(k92 + x14)))/k161),
  Eq(Derivative(x18, t), (1*k162*(k31*x12*x40/((k32 + x12)*(k33 + x40)) - k34*x41*x18/((k35 + x41)*(k36 + x18))) + 1*k162*(k42*x12*k171 - k43*x18) + 1*k162*k44*x12*x41/((k45 + x12)*(k46 + x41)) + 1*k162*k47*x12*x43/((k48 + x12)*(k49 + x43)) + 1*k162*k50*x12*x44/((k51 + x12)*(k52 + x44)) + (-1)*k162*(k53*x18/(k54 + x18) - k55*x19/(k56 + x19)))/k162),
  Eq(Derivative(x19, t), (1*k162*(k53*x18/(k54 + x18) - k55*x19/(k56 + x19)) + (-1)*k162*(k57*x19/(k58 + x19) - k59*x20/(k60 + x20)))/k162),
  Eq(Derivative(x20, t), ((-1)*k162*k29*x20/(k30 + x20) + 1*k162*(k37*x12*x42/((k38 + x12)*(k39 + x42)) - k40*x20/(k41 + x20)) + 1*k162*(k57*x19/(k58 + x19) - k59*x20/(k60 + x20)))/k162),
  Eq(Derivative(x21, t), (1*k160*90*x25 + 2*k160*135/2*x24 + (-1)*k160*1/10*x21 + 1*k160*Piecewise((k150, And(Le(7, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 10))), (k149, And(Le(12, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 15))), (k148, And(Le(18, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 21))), (k151, True))*k156 + (-1)*k161*(k20*x21/(k21 + x21) - k22*x30))/k160),
  Eq(Derivative(x22, t), (1*k160*90*x25 + 2*k160*135/2*x24 + (-1)*k160*1/10*x22 + 1*k160*Piecewise((k150, And(Le(7, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 10))), (k149, And(Le(12, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 15))), (k148, And(Le(18, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 21))), (k151, True))*k157 + (-1)*k161*(k17*x22/(k18 + x22) - k19*x27))/k160),
  Eq(Derivative(x23, t), (1*k160*90*x25 + 2*k160*135/2*x24 + (-1)*k160*1/4*x23 + (-1)*k160*1/10*x23 + 1*k160*Piecewise((k150, And(Le(7, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 10))), (k149, And(Le(12, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 15))), (k148, And(Le(18, t - 24*floor(t/24)), Le(t - 24*floor(t/24), 21))), (k151, True))*k158 + (-1)*k161*k15*x23/(k16 + x23))/k160),
  Eq(Derivative(x24, t), ((-1)*k160*135/2*x24 + (-1)*k160*15/2*x24 + 1*k161*k11*x31/(k12 + x31) + 1*k161*k13*x31/(k14 + x31))/k160),
  Eq(Derivative(x25, t), ((-1)*k160*90*x25 + (-1)*k160*7/10*x25 + 1*k161*k6*x32/(k7 + x32) + 1*k161*k8*x32**k9/(k10**k9 + x32**k9))/k160),
  Eq(Derivative(x26, t), (1*k161*k80*x16*k164/((k81 + x16)*(k82 + k164)) + (-1)*k161*k99*x16*x26/((k100 + x16)*(k101 + x26)))/k161),
  Eq(Derivative(x27, t), (1*k161*(k17*x22/(k18 + x22) - k19*x27) + (-1)*k161*k130*(x28*x27 - x29/k131)/(k132*k133 + x27*k132 + x28*(k133*(1 + x32/k134) + x27) + x29/k135 + x32/k134)*(k169 + k136)/(k74 + k136) + (-1)*k161*7/100*x27)/k161),
  Eq(Derivative(x28, t), (1*k161*k15*x23/(k16 + x23) + 1*k161*k128*x33/(k129 + x33) + (-1)*k161*k130*(x28*x27 - x29/k131)/(k132*k133 + x27*k132 + x28*(k133*(1 + x32/k134) + x27) + x29/k135 + x32/k134)*(k169 + k136)/(k74 + k136) + (-1)*k161*7/20*x28**2/200)/k161),
  Eq(Derivative(x29, t), (1*k161*k130*(x28*x27 - x29/k131)/(k132*k133 + x27*k132 + x28*(k133*(1 + x32/k134) + x27) + x29/k135 + x32/k134)*(k169 + k136)/(k74 + k136) + (-1)*k161*k137*(x30*x29 - x32/k138)/(k139*k140 + x29*k139 + x30*(k140 + x29) + x32/k141))/k161),
  Eq(Derivative(x30, t), (1*k161*(k20*x21/(k21 + x21) - k22*x30) + 1*(k67*x41/(k68 + x41)*k162*1/3 - k69*x30/(k70 + x30)*k161) + 1*k161*(k86*x11*x35/((k32 + x11)*(k33 + x35)) - k87*x30*x14/((k35 + x30)*(k36 + x14))) + (-1)*k161*k113*x37*x30/((k114 + x37)*(k115 + x30))*1/(1 + x36/k116)*24/5/(7/20 + x13) + (-1)*k161*k137*(x30*x29 - x32/k138)/(k139*k140 + x29*k139 + x30*(k140 + x29) + x32/k141))/k161),
  Eq(Derivative(x31, t), ((-1)*k161*k11*x31/(k12 + x31) + (-1)*k161*k13*x31/(k14 + x31) + 1*k161*k142*(x32/(k143 + x32))**2*k169/(k144 + k169) + (-1)*k161*k145*x31*k165/((k146 + x31)*(k147 + k165)) + (-1)*k161*1/10*x31)/k161),
  Eq(Derivative(x32, t), ((-1)*k161*k6*x32/(k7 + x32) + (-1)*k161*k8*x32**k9/(k10**k9 + x32**k9) + 1*k161*k137*(x30*x29 - x32/k138)/(k139*k140 + x29*k139 + x30*(k140 + x29) + x32/k141) + (-2)*k161*k142*(x32/(k143 + x32))**2*k169/(k144 + k169) + 2*k161*k145*x31*k165/((k146 + x31)*(k147 + k165)) + (-1)*k161*1/500*x32)/k161),
  Eq(Derivative(x33, t), (1*k161*k124*x34*x35/((k125 + x34)*(k126 + x35))*((30/(10259/100))**2 + 1)/((30/(x37 + x36))**2 + 1)*(k169 + k127)/(k74 + k127) + (-1)*k161*k128*x33/(k129 + x33))/k161),
  Eq(Derivative(x34, t), ((-1)*k161*k71*x13*x34/((k72 + x13)*(k73 + x34))*(k74 + k75)/(k169 + k75) + (-1)*k161*exp(-21/10000*(x37 + x36))*exp(21/10000*513/5)*k102*x34*k166/((k103 + x34)*(k104 + k166))*(k74 + k105)/(k169 + k105) + 1*k161*(k120*x36/(k121 + x36) - k122*x34/(k123 + x34)) + (-1)*k161*k124*x34*x35/((k125 + x34)*(k126 + x35))*((30/(10259/100))**2 + 1)/((30/(x37 + x36))**2 + 1)*(k169 + k127)/(k74 + k127))/k161),
  Eq(Derivative(x35, t), (1*k161*(k23*x2/(k24 + x2) - k25*x35) + 1*(k61*x40/(k62 + x40)*k162/3 - k63*x35/(k64 + x35))*k161 + (-1)*k161*(k86*x11*x35/((k32 + x11)*(k33 + x35)) - k87*x30*x14/((k35 + x30)*(k36 + x14))) + (-1)*k161*6/5*x35 + (-1)*k161*k124*x34*x35/((k125 + x34)*(k126 + x35))*((30/(10259/100))**2 + 1)/((30/(x37 + x36))**2 + 1)*(k169 + k127)/(k74 + k127))/k161),
  Eq(Derivative(x36, t), (1*k161*k113*x37*x30/((k114 + x37)*(k115 + x30))*1/(1 + x36/k116)*24/5/(7/20 + x13) + 1*k161*k117*x37/(k118*(1 + x36/k119) + x37) + (-1)*k161*(k120*x36/(k121 + x36) - k122*x34/(k123 + x34)))/k161),
  Eq(Derivative(x37, t), (1*k161*k106*x38/(k107 + x38)*(23/100 + 4/5*exp(-13/5000*x37))*(k108 + 6671/100)/(k108 + x31) + 1*k161*k109*x38**(121/100)/(k110 + x38**(121/100))*(1 + 36/5*x37**2/(k111**2 + x37**2))*(k112 + 6671/100)/(k112 + x31) + (-1)*k161*k113*x37*x30/((k114 + x37)*(k115 + x30))*1/(1 + x36/k116)*24/5/(7/20 + x13) + (-1)*k161*k117*x37/(k118*(1 + x36/k119) + x37))/k161),
  Eq(Derivative(x38, t), (1*k161*(k26*x1/(k27 + x1) - k28*x38) + 1*k161*k71*x13*x34/((k72 + x13)*(k73 + x34))*(k74 + k75)/(k169 + k75) + 1*k161*exp(-21/10000*(x37 + x36))*exp(21/10000*513/5)*k102*x34*k166/((k103 + x34)*(k104 + k166))*(k74 + k105)/(k169 + k105) + (-1)*k161*k106*x38/(k107 + x38)*(23/100 + 4/5*exp(-13/5000*x37))*(k108 + 6671/100)/(k108 + x31) + (-1)*k161*k109*x38**(121/100)/(k110 + x38**(121/100))*(1 + 36/5*x37**2/(k111**2 + x37**2))*(k112 + 6671/100)/(k112 + x31))/k161),
  Eq(Derivative(x39, t), (1*(k65*x42*k162/3 - k66*x39*k161) + (-1)*k161*k83*x11*x39/((k84 + x11)*(k85 + x39)))/k161),
  Eq(Derivative(x40, t), ((-1)*k162*(k31*x12*x40/((k32 + x12)*(k33 + x40)) - k34*x41*x18/((k35 + x41)*(k36 + x18))) + (-3)*(k61*x40/(k62 + x40)*k162/3 - k63*x35/(k64 + x35))*k161)/k162),
  Eq(Derivative(x41, t), (1*k162*(k31*x12*x40/((k32 + x12)*(k33 + x40)) - k34*x41*x18/((k35 + x41)*(k36 + x18))) + (-1)*k162*k44*x12*x41/((k45 + x12)*(k46 + x41)) + 1*k162*k47*x12*x43/((k48 + x12)*(k49 + x43)) + (-3)*(k67*x41/(k68 + x41)*k162*1/3 - k69*x30/(k70 + x30)*k161))/k162),
  Eq(Derivative(x42, t), ((-1)*k162*(k37*x12*x42/((k38 + x12)*(k39 + x42)) - k40*x20/(k41 + x20)) + (-3)*(k65*x42*k162/3 - k66*x39*k161))/k162),
  Eq(Derivative(x43, t), ((-1)*k162*k47*x12*x43/((k48 + x12)*(k49 + x43)) + 1*k162*k50*x12*x44/((k51 + x12)*(k52 + x44)) + 1*k161*k113*x37*x30/((k114 + x37)*(k115 + x30))*1/(1 + x36/k116)*24/5/(7/20 + x13))/k163),
  Eq(Derivative(x44, t), ((-1)*k162*k50*x12*x44/((k51 + x12)*(k52 + x44)) + 1*k161*exp(-21/10000*(x37 + x36))*exp(21/10000*513/5)*k102*x34*k166/((k103 + x34)*(k104 + k166))*(k74 + k105)/(k169 + k105))/k163) ]